N-BOC-2-AMINOISOBUTYRIC ACID
N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine
CAS: 30992-29-1
Molecular Formula: C9H17NO4
N-BOC-2-AMINOISOBUTYRIC ACID - Names and Identifiers
| Name | N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine |
| Synonyms | Boc-Aib-OH RARECHEM EM WB 0052 IFLAB-BB F2108-0194 Boc-2-aminoisobutyric acid N-BOC-2-AMINOISOBUTYRIC ACID N-(tert-Butoxycarbonyl)-2-methylalanine N-(tert-Butoxycarbonyl)-2-methyl-L-alanine N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine 2-[(tert-butoxycarbonyl)amino]-2-methylpropanoate 2-Methyl-2-(tert-butoxycarbonylamino)propionic acid N-ALPHA-T-BUTOXYCARBONYL-ALPHA-AMINOISOBUTYRIC ACID Alanine, N-[(1,1-dimethylethoxy)carbonyl]-2-methyl- |
| CAS | 30992-29-1 |
| EINECS | 250-421-0 |
| InChI | InChI=1/C9H17NO4/c1-8(2,3)14-7(13)10-9(4,5)6(11)12/h1-5H3,(H,10,13)(H,11,12)/p-1 |
| InChIKey | VLHQXRIIQSTJCQ-LURJTMIESA-N |
N-BOC-2-AMINOISOBUTYRIC ACID - Physico-chemical Properties
| Molecular Formula | C9H17NO4 |
| Molar Mass | 203.24 |
| Density | 1.1886 (rough estimate) |
| Melting Point | 118-122°C |
| Boling Point | 341.54°C (rough estimate) |
| Flash Point | 151.9°C |
| Vapor Presure | 3.97E-05mmHg at 25°C |
| Appearance | White crystal |
| Color | White |
| BRN | 1953772 |
| pKa | 4.11±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.4315 (estimate) |
| MDL | MFCD00042973 |
N-BOC-2-AMINOISOBUTYRIC ACID - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29241990 |
| Hazard Class | IRRITANT |
N-BOC-2-AMINOISOBUTYRIC ACID - Introduction
N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine, chemical name is N-[(1,1-dimethylethoxy)carbonyl]-2-methylalanine, it is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: A white crystalline solid.
-molecular formula: C9H17NO4.
-Molecular weight: 203.24g/mol.
-Melting point: About 60-62°C.
-Solubility: Soluble in organic solvents such as ether, chloroform and alcohol, insoluble in water.
Use:
N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine is a reagent commonly used in organic synthesis and is mainly used as an intermediate in peptide synthesis. It can protect the amino group, and has good stability and selectivity. In drug development and chemical synthesis, N-[(1,1-dimethyllethoxy) carbonyl]-2-methyl-alanine can be used in the synthesis of synthetic polypeptides, drug ligands, and natural products.
Method:
The preparation of N-[(1,1-dimenthylethoxy) carbonyl]-2-methyl-alanine is generally carried out by the following steps:
1.2-methyl alanine is reacted with dimethyl carbonate anhydride to generate N-Boc-2-methyl alanine.
2. Reaction of N-Boc-2-methylalanine with isobutylene alcohol to produce N-[(1,1-dimethyllethoxy) carbonyl]-2-methyl-alanine.
Safety Information:
N-[(1,1-dimenthylethoxy) carbonyl]-2-methyl-alanine is relatively safe under normal operating conditions, but some basic safety precautions still need to be observed:
-Personal protective equipment such as lab gloves and goggles should be used during operation.
-Avoid direct contact with skin and inhalation of its dust or solution.
-When storing, it should be sealed and stored in a dry, cool place, away from heat and flame.
-Detailed safe operation methods and guidelines for handling waste can be obtained from the substance's safety data sheet (MSDS).
Nature:
-Appearance: A white crystalline solid.
-molecular formula: C9H17NO4.
-Molecular weight: 203.24g/mol.
-Melting point: About 60-62°C.
-Solubility: Soluble in organic solvents such as ether, chloroform and alcohol, insoluble in water.
Use:
N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine is a reagent commonly used in organic synthesis and is mainly used as an intermediate in peptide synthesis. It can protect the amino group, and has good stability and selectivity. In drug development and chemical synthesis, N-[(1,1-dimethyllethoxy) carbonyl]-2-methyl-alanine can be used in the synthesis of synthetic polypeptides, drug ligands, and natural products.
Method:
The preparation of N-[(1,1-dimenthylethoxy) carbonyl]-2-methyl-alanine is generally carried out by the following steps:
1.2-methyl alanine is reacted with dimethyl carbonate anhydride to generate N-Boc-2-methyl alanine.
2. Reaction of N-Boc-2-methylalanine with isobutylene alcohol to produce N-[(1,1-dimethyllethoxy) carbonyl]-2-methyl-alanine.
Safety Information:
N-[(1,1-dimenthylethoxy) carbonyl]-2-methyl-alanine is relatively safe under normal operating conditions, but some basic safety precautions still need to be observed:
-Personal protective equipment such as lab gloves and goggles should be used during operation.
-Avoid direct contact with skin and inhalation of its dust or solution.
-When storing, it should be sealed and stored in a dry, cool place, away from heat and flame.
-Detailed safe operation methods and guidelines for handling waste can be obtained from the substance's safety data sheet (MSDS).
Last Update：2024-04-09 02:00:45
Supplier List
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Anamorelin Impurity 1 Visit Supplier Webpage Request for quotationCAS: 30992-29-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Boc-Aib-OH Visit Supplier Webpage Request for quotationCAS: 30992-29-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Anamorelin Impurity 1 Visit Supplier Webpage Request for quotationCAS: 30992-29-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: N-[(1,1-dimethylethoxy)carbonyl]-2-methyl-alanine Request for quotationCAS: 30992-29-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Boc-Aib-OH Visit Supplier Webpage Request for quotationCAS: 30992-29-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History